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In preclinical research on drug addiction and the GLP-1 system, most studies have used exendin-4, a short-acting GLP-1 receptor agonist, as a treatment
Topiramate may cause decreased sweating and increased body temperature (fever)
Tirzepatide was also associated with dose-dependent positive changes in lipids, with a reduction in triglycerides and increases in HDL cholesterol
Other GLP-1 receptor agonists and various weight loss interventionswhether pharmacological, dietary, or surgicalare also associated with increased gallbladder-related risks, though the magnitude may vary by approach and agent
Selective brain entry of lipid nanoparticles in haemorrhagic stroke is linked to biphasic blood-brain barrier disruption
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